Publications
Once I fix the format I will place the publication list from your CV here.
1. J.T. Brosnan, H.A. Krebs and D.H. Williamson. Biochem. J. 117, 91 (1970). "Effects of ischaemia on metabolite concentrations in rat liver".2. P. Lund, J.T. Brosnan and L.V. Eggleston in "Essays in cell metabolism" (1970) p. 167 Eds. W. Bartley, H.L. Kornberg and J.R. Quayle, Wiley-Interscience, London. "The regulation of ammonia metabolism in mammalian tissues".
3. D.A. Hems and J.T. Brosnan. Biochem. J. 120, 105 (1970). "Effects of ischaemia on content of metabolites in rat liver and kidney in vivo".
4. D.A. Hems and J.T. Brosnan. Biochem. J. 123, 391 (1971). "Effects of metabolic acidosis and starvation on the content of intermediary metabolites in rat kidney".
5. J.T. Brosnan and I.B. Fritz. Biochem. J. 125, 94 (1971). "The permeability of mitochondria to carnitine and acetylcarnitine".
6. J.T. Brosnan and I.B. Fritz. Can. J. Biochem. 49, 1296 (1971). "The oxidation of fatty-acyl derivatives by mitochondria from bovine fetal and calf hearts".
7. J.T. Brosnan, B. Kopec and I.B. Fritz. J. Biol. Chem. 248, 4075 (1973). "The localization of carnitine palmitoyltransferase on the inner membrane of bovine liver mitochondria".
8. J. Kalra and J.T. Brosnan. FEBS Letters 37, 325 (1973). "Localization of glutaminase in rat liver".
9. J.T. Brosnan and D.H. Williamson. Biochem. J. 138, 453 (1974). "Mechanisms for the formation of alanine and aspartate in rat liver in vivo after administration of ammonium chloride".
10. J. Kalra and J.T. Brosnan. J. Biol. Chem. 249, 3255 (1974). "The subcellular localization of glutaminase isoenzymes in rat kidney cortex".
11. D.H. Williamson and J.T. Brosnan in "Methoden der Enzymatischen Analyse", Vol. II, P. 2187 (1971). Ed. H.-U. Bergmeyer, Verlag-Chemie Weinheim. "Concentrations of metabolites in animal tissue".
12. I.B. Fritz, B. Kopec and J.T. Brosnan in "Regulation of Hepatic Metabolism", Alfred Benzon Symposium VI (1974). Eds. F. Lundquist and Tygstrup. Academic Press - New York. "Localization of carnitine palmitoyltransferases on inner membranes of mitochondria, and their possible role in the regulation of fatty acyl group translocation".
13. J. Kalra and J.T. Brosnan. Can. J. Biochem. 52, 762 (1974). "Localization of phosphate-independent glutaminase in the brush border of rat kidney cortex".
14. J.T. Brosnan and J. Kalra. Biochem. Soc. Trans 2, 1341 (1974). "Phosphate- independent glutaminase from rat kidney cortex".
15. J.T. Brosnan in "The Urea Cycle", 1976. Eds. S. Grisoila, F. Mayor and F. Candela-Baguena. Academic Press, New York. "The regulation of hepatic ammonia concentrations". p. 443.
16. E.J. Squires, D.E. Hall and J.T. Brosnan. Biochem. J. 60, 125 (1976). "Arteriovenous differences for amino acids and lactate across kidneys of normal and acidotic rats".
17. J.T. Brosnan and B. Hall. Biochem. J. 164, 331 (1977). "The transport and metabolism of glutamine by kidney-cortex mitochondria from normal and acidotic rats".
18. E.J. Squires and J.T. Brosnan. Analyt. Biochem., 84, 473 (1978). "Determination of specific radioactivity in 14C-labelled glutamic acid and glutamine".
19. D.M. Parry and J.T. Brosnan. Glutamine metabolism during induction of, and recovery from, metabolic acidosis in the rat. Biochem. J. 174, 387 (1978).
20. J.T. Brosnan, P. McPhee, B. Hall and D.M. Parry. Renal glutamine metabolism in rats fed high-protein diets. Amer. J. Physiol. 235, E261 (1978).
21. J.T. Brosnan. Pathways of carbon flux in gluconeogenesis. This is part of a symposium on "Carbon fluxes in the synthesis of glucose and glycogen" at the 1979 FASEB meeting at Dallas. Fed. Proc. 41, 91 (1981).
22. J.T. Brosnan, W. Redmond, D. Morgan and P. Whalen. The malate/2-oxo-glutarate transporter in mitochondria from rat kidney cortex: increased activity in metabolic acidosis. Internat. J. Biochem. 12, 131 (1980).
23. J.T. Brosnan and M.E. Brosnan. Dietary Protein, Metabolic Acidosis and calcium balance. Advances in Nutritional Research Vol. 4, p. 77, Ed. H.H. Draper, Plenum Press, 1980.
24. M.E. Brosnan, S.A. Colbourne and J.T. Brosnan in "Short-term regulation of urea synthesis in vivo: Facts and Speculations". In "Short-term regulation of liver metabolism" p.313 eds. L. Hue and G. Van de Werve. Elsevier 1980.
25. D.M. Parry and J.T. Brosnan. "Renal phosphoenolpyruvate carboxykinase during perturbations of acid-base homeostasis in rats. Immunochemical studies". Can. J. Biochem. 58, 1298 (1980).
26. K.C. Man, B. Hall and J.T. Brosnan. "Effects of 3-amino picolinic acid on renal ammoniagenesis in the rat. Biochem. Pharmacol. 30, 1895 (1981).
27. D.M. Parry, B. Hall and J.T. Brosnan. "Renal metabolite concentrations and the activities of glutaminase and glutamate dehydrogenase during recovery from metabolic acidosis in the rat". Can. J. Biochem. 59, 871 (1981).
28. J.T. Brosnan and D.M. Parry. "Accelerated recovery from metabolic acidosis in "Contributions to Nephrology" Vol. 31, p. 135. Published by S. Karger, A.G. Basel (1982).
29. K.P. Coolbear, G.R. Herzberg and J.T. Brosnan. "Subcellular localization of chicken liver xanthine dehydrogenase. A possible source of cytoplasmic reducing equivalents. Biochem. J. 202, 55 (1982).
30. K.C. Man and J.T. Brosnan. "Inhibition of medium and short-chain fatty acid oxidation in rat heart mitochondria by dichloroacetate". Metabolism 31, 744, 1982.
31. F.H. Epstein, J.T. Brosnan. J.D. Tange and B.D. Ross. "Improved function with amino acids in isolated perfused kidney: role of glutathione". Amer. J. Physiol. 243, F284 (1982).
32. J.T. Brosnan, K.-C. Man, D.E. Hall, S.A. Colbourne and M.E. Brosnan. "Interorgan Metabolism of Amino Acids in the Streptozotocin-Diabetic Ketoacidotic Rat". Amer. J. Physiol. 244, E151 (1983).
33. E.J. Squires and J.T. Brosnan. "Measurements of the turnover rate of glutamine in normal and acidotic rats". Biochem. J. 210, 277 (1983).
34. D.A. Tinker, J.T. Brosnan and G.R. Herzberg. "Avian phosphoenolpyruvate carboxykinase: effect of age, starvation and photoperiod". Int. J. Biochem. 15, 1255 (1983).
35. D.A. Tinker, J.T. Brosnan and G.R. Herzberg. "Phosphoenol pyruvate carboxykinase is a nuclear enzyme in rats and chicken". Int. J. Biochem. 15, 1473 (1983)".
36. J.T. Brosnan, R.G.P. Forsey and M.E. Brosnan. "Uptake of tyrosine and leucine in vivo by brain of diabetic and control rats". Amer. J. Physiol. 247, 450 (1984).
37. D.A. Tinker, J.T. Brosnan and G.R. Herzberg. "Metabolite levels in control and anoxic chicken liver while employing a technique for artificial respiration in birds. Comp. Biochem., 77B, 115 (1984).
38. D.A. Tinker, J.T. Brosnan and G.R. Herzberg. "Metabolite levels in fed and fasted chicken liver and kidney while employing a technique for artificial respiration in birds. Comp. Biochem. 77B, 119 (1984).
39. M. Lowry, D. Hall and J.T. Brosnan. "Serine synthesis in rat kidney". Amer. J. Physiol. 250, F649-F658, 1986.
40. J.T. Brosnan, H. Lanctin, E.T. Quarcoo and B.D. Ross. "Glutamine synthesis in the perfused kidney and in isolated cortical tubules": regulation by pH". Clinical Science 69, 701-707, 1985.
41. A. Fine, J.T. Brosnan and G.R. Herzberg. "Release of lactate by the liver in metabolic acidosis in vivo". Metabolism 33, 393 (1984).
42. M. Lowry, B. Hall, D.E. Hall and J.T. Brosnan. "Pathways of serine synthesis in the rat kidney". Contributions to Nephrology. Karger (Basel) 47, 203 (1985).
43. H. Lanctin, E.T. Quarcoo and J.T. Brosnan. "Acute regulation of renal glutamine synthesis by pH in rat and guinea pig". Contributions to Nephrology. Karger (Basel) 47, 186 (1985)
44. M. Lowry, B. Hall, D.E. Hall and J.T. Brosnan. "Pathways of serine synthesis in the rat kidney". Contributions to Nephrology. Karger (Basel) 47, 203 (1985).
45. H. Lanctin, E.T. Quarcoo and J.T. Brosnan. "Acute regulation of renal glutamine synthesis by pH in rat and guinea pig". Contributions to Nephrology. Karger (Basel) 47, 186 (1985).
46. J.T. Brosnan and K. Reid. "Inhibition of palmitoylcarnitine oxidation by pyruvate in rat heart mitochondria". Metabolism 34, 588 (1985).
47. K.C. Man and J.T. Brosnan. "A radiochemical assay for mitochondrial acetyl-CoA synthase and octanoyl-CoA synthase from rat heart". Int. J. Biochem. 16, 1341 (1985).
48. M.E. Brosnan, A. Lowry, Y. Wasi, M. Lowry and J.T. Brosnan. "Regional and subcellular distribution of enzymes of branched-chain amino acid metabolism in brains of normal and diabetic rats". Can. J. Physiol. Pharmacol. 63, 1234 (1985).
49. M. Lowry, D.E. Hall and J.T. Brosnan. "Metabolism of glycine and hydroxyproline- containing peptides by the isolated perfused rat kidney". Biochem. J. 229, 545 (1985).
50. M. Lowry, D.E. Hall and J.T. Brosnan. "Renal glycine cleavage enzyme complex: Increased activity in metabolic acidosis". Biochem. J. 231, 477 (1985).
51. J.T. Brosnan. "Studying renal amino acid metabolism in vivo - How and why? Bull. Can. Biochem. Soc. 22, 20 (1985).
52. M. Lowry, D.E. Hall and J.T. Brosnan. "Hydroxyproline metabolism by the rat kidney". Metabolism 34, 955 (1985).
53. D.A. Tinker, J.T. Brosnan and G.R. Herzberg. "Interorgan metabolism of amino acids, glucose, lactate, glycerol and uric acid in the domestic fowl (Gallus domesticus). Biochem. J. 240, 829 (1986).
54. J. Letto, M.E. Brosnan and J.T. Brosnan. "Valine metabolism: gluconeogenesis from 3-hydroxyisobutyrate". Biochem. J. 240, 900 (1986).
55. M.E. Brosnan, A. Lowry and J.T. Brosnan. "Diabetes increases the active fraction of branched-chain 2-oxoacid dehydrogenase in rat brain". Diabetes 35, 1041 (1986).
56. M. Lowry, D.E. Hall, M.S. Hall and J.T. Brosnan. "Renal metabolism of amino acids in vivo. The effects of cysteamine, mercaptopicolinic acid and AT-125 on serine and glycine fluxes". Amer. J. Physiol. 252, F304 (1987).
57. R.G.P. Forsey, K. Reid and J.T. Brosnan. "Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart". Can. J. Physiol. Pharmacol. 65. 401 (1987).
58. J.T. Brosnan, M. Lowry, P. Viney, A. Gougoux and M.L. Halperin. "Renal ammonium production - une vue Canadienne". Can. J. Physiol. Pharmacol. 65, 489 (1987).
59. M.L. Halperin, R.L. Jungas, S. Cheema-Dhadli and J.T. Brosnan, "Disposal of the daily acid load: an integrated function of the liver, lungs and kidneys". T.I.B.S. 12, 197 (1987).
60. J.T. Brosnan, The Borden Lecture "The role of the kidney in amino acid metabolism and nutrition". Can. J. Physiol. Pharmacol. 65, 2355 (1987).
61. J.T. Brosnan, P. Vinay, A. Gougoux and M.L. Halperin "Renal ammonium production and its implications for acid-base balance" in "pH Homeostasis: Mechanisms and Control", Ed. D. Haussinger, Academic Press (1988).
62. G.R. Herzberg, J.T. Brosnan, B. Hall and M. Rogerson "Gluconeogenesis in liver and kidney of common murre (Uria aalge). Amer. J. Physiol. 254, R903 (1988).
63. M. Jois, D. E. Hall and J. T. Brosnan, "Serine Synthesis by the Rat Kidney. Contrib. Nephrol. 63, 136 (1988).
64. M. Jois, B. Hall, K. Fewer and J.T. Brosnan "Regulation of Hepatic Glycine Catabolism by glucagon," J. Biol. Chem. 264, 3347 (1989).
65. J.T. Brosnan, M.E. Brosnan, "Ammonium and Organic Cations" in Monovalent cations in biological systems (Ed. C. Pasternak) CRC Press (1989).
66. J. T. Brosnan and B. Hall. "Renal Serine Production in vivo: effects of dietary manipulation of serine status." Can. J. Physiol. Pharmacol. 67, 1048-1061 (1989).
67. M. Jois, B. Hall, V. M. Collett and J.T. Brosnan. "Flux through glycine cleavage system in isolated hepatocytes. Effects of glucagon, cyclic AMP and calcium." Biochem. and Cell Biol. 68, 543-546 (1990).
68. M. Jois, B. Hall and J.T. Brosnan. "Stimulation of glycine metabolism in isolated perfused rat liver by calcium mobilizing hormones and in isolated rat liver mitochondria by submicromolar concentrations of calcium." J. Biol. Chem. 265, 1246-1248 (1990).
69. J.T. Brosnan, M. Jois and B. Hall. "Hormonal regulation of glycine metabolism" in "Amino Acids: Chemistry, Biology and Medicine," Ed. G. Lubec and G.A. Rosenthal; Publ. Escom, Leiden, Netherlands pp. 896-902.
70. J. Letto, J.T. Brosnan and M.E. Brosnan. "Oxidation of 2-oxoisocoproate and 2-oxoisovalerate by the perfused rat heart. Interactions with fatty acid oxidation." Biochem. Cell Biol. 68, 260-265 (1990).
71. S.N. Dhanakoti, J.T. Brosnan, G.R. Herzberg and M.E. Brosnan. "Renal Arginine Synthesis: Studies in vitro and in vivo". Amer. J. Physiol 259, E437-E442 (1990).
72. R.L. Jungas, M.L. Halperin and J.T. Brosnan. "A quantitative analysis of amino acid oxidtation and related gluconeogenesis in man". Physiol. Rev. 72, 419-447 (1992).
73. S.N. Dhanakoti, M.E. Brosnan, G.R. Herzberg and J.T. Brosnan. "Cellular and subcellular localization of enzymes of arginine metabolism in rat kidney". Biochem. J. 282, 369-375 (1992).
74. S.N. Dhanakoti, J.T. Brosnan, M.E. Brosnan and G.R. Herzberg. "Net renal arginine flux in rats is not affected by dietary arginine or dietary protein intake". J. Nutrition 122, 1127-1134, (1992).
75. H.S. Ewart, M. Jois and J.T. Brosnan. "Rapid stimulation of the hepatic glycine cleavage system in rats fed a single high protein meal". Biochem. J. 283, 441-447, (1992).
76. M. Jois, S.E. Ewart and J.T. Brosnan. "Regulation of glycine catabolism in rat liver mitochondria". Biochem. J. 283, 435-439, (1992).
77. G. Wu and J.T. Brosnan. "Macrophages can convert citrulline to arginine". Biochem. J. 281, 45-48 (1992).
78. J.T. Brosnan, S.N. Dhanakoti, S.M. Skanes, G. Wu, G.R. Herzberg and M.E. Brosnan, "Endogenous arginine synthesis" in "The Biology of Nitric Oxide" Eds. S. Moncada, M.A. Marletta, J.B. Hibbs Jr., and E.A. Higgs. Vol. 2, pp. 32-34. Portland Press (1992).
79. H.S. Ewart and J.T. Brosnan "Rapid Activation of Hepatic Glutaminase in rats fed in a single high-protein Meal", Biochem. J. 293, 339-344 (1993).
80. J.T. Brosnan, H.S. Ewart, S.A. Squires, S.H. Day, Z. Kovacevic and M.E. Brosnan. " Hormonal and dietary control of hepatic glutamine catabolism". Contrib. Nephrol. 110, 109-114 (1994).
81. J.T. Brosnan and D. Qian. "Endotoxin-induced increase in liver mass and hepatocyte volume". Biochem. Soc. Trans. 22, 529-532 (1994).
82. J.T. Brosnan and D.Qian “Endotoxin-induced increase in liver mass and hepatocyte volume” Biochem. Soc. Trans. 22: 529-532 (1994).
83. Z. Kovacevic, S.H. Day, V. Collett, J.T. Brosnan and M.E. Brosnan. "Activation of hepatic glutaminase by spermine". Biochem. J. 305: 837-841 (1995).
84. J.T. Brosnan, H.S. Ewart and S.A. Squires. "Hormonal Control of Hepatic Glutaminase". Advances in Enzyme Regulation, 35: 131-146 (1995).
85. A. Bostom, J.T. Brosnan, B. Hall, M. Nadeau and J. Selhub. "Net uptake of plasma homocysteine by the rat kidney in vivo". Atherosclerosis 116: 59-62 (1995).
86. H.S. Ewart, D. Qian and J.T. Brosnan. "Activation of hepatic glutaminase in the Endotoxin - Lactated rat". J. Surg. Res. 59: 245-249 (1995).
87. D. Qian and J.T. Brosnan. "Administration of E. coli endotoxin to rats increases liver mass and hepatocyte volume in vivo". Biochem. J. 313: 479-486 (1996).
88. J.T. Brosnan, M.E. Brosnan, R. Charron and I. Nissim. "A mass isotopomer study of urea and glutamine synthesis from 15N-labelled ammonia in the perfused rat liver". J. Biol. Chem. 271: 16199-16207 (1996).
89. I. Nissim, M. Yudkoff and J.T. Brosnan. “Regulation of [15N] urea synthesis from [5-15N] glutamine. Role of pH, hormones and pyruvate.” J.Biol.Chem. 271: 31234-31244 (1996).
90. J.D. House, M.E. Brosnan and J.T. Brosnan. “Renal homocysteine metabolism”. Contrib.Nephrol. 121: 79-84 (1997).
91. S.A. Squires, H.S. Ewart, C. McCarthy, M.E. Brosnan and J.T. Brosnan. “Regulation of hepatic glutaminase in the streptozotocin-diabetic rat”. Diabetes (1997).
92. J.T. Brosnan, M.E. Brosnan, R. Charron and I. Nissim. “Incorporation of 15N-labelled precursors into urea isotopomers”. Contrib.Nephrol. 121: 156-162 (1997).
93. G.M. Mabrouk and J.T. Brosnan. “Activation of the hepatic glycine cleavage enzyme system by glucagon and glucagon-related peptides”. Can.J.Physiol.Pharmacol 75:1096-1100, (1997).
94. G.M. Mabrouk, M. Jois and J.T. Brosnan. “Cell signalling and the hormonal stimulation of the hepatic glycine cleavage enzyme system by glucagon”. Biochem. J. 330:759-763 (1997).
95. J.D. House, M.E. Brosnan and J.T. Brosnan. “Characterization of homocysteine metabolism in the rat kidney”. Biochem. J. 328: 287-292, (1997).
96. D.O’Sullivan, J.T. Brosnan and M.E. Brosnan. “Hepatic zonation of the catabolism of arginine and ornithine in the perfused rat liver”. Biochem. J. 330:627-632 (1997).
97. J.T. Brosnan “Three cheers for metabolism” Bulletin of the Canadian Society of Biochemistry, Molecular and Cellular Biology, pp 58-60 (1997).
98. J.D. House, M.E. Brosnan and J.T. Brosnan. “Renal uptake and excretion of homocysteine in rats with acute hyperhomocysteinemia”. Kidney Internat. 54:1601-1607 (1998).
99. R.L. Jacobs, J.D. House, M.E. Brosnan and J.T. Brosnan. “Effects of Streptozotocin induced diabetes and of insulin treatment on homocysteine metabolism in the rat”. Diabetes, 47: 1967-1970 (1998).
100. J.T. Brosnan. “Metabolic Needs for glucose and the role of gluconeogenesis”. Europ. J. Clin. Nutr., 53: Supl7: S107-S111 (1999).
101. J.D House, R.L. Jacobs, L.M. Stead, M.E. Brosnan and J.T. Brosnan. “Regulation of homocysteine metabolism”. Advances Enz. Regul., 39: 69-91 (1999).
102. D.M. Bier, J.T. Brosnan, J.P. Flatt, R.W. Hanson, W. Heird, M.K. Hellerstein, E. Jequuier, S. Kalhan, B. Koletzko, I. Macdonald, O. Owen, and R. Uauy. “Report of the IDECG Working Group on lower and upper limits of carbohydrate and fat intake. International Dietary Energy Consultative Group”, Europ. J. Clin. Nutr. 53, Suppl1: S177-S178 (1999).
103. I. Nissim, M.E. Brosnan, M. Yudkoff and J.T. Brosnan. “Studies of hepatic glutamine metabolism in the perfused rat liver with 15N-labelled glutamine”. J. Biol. Chem. 274: 28958-28965 (1999).
104. J.T. Brosnan. “Glutamate, at the interface between amino acid and carbohydrate metabolism”. J. Nutr. 130, Suppl 4: 988S-990S (1999).
105. D. O’Sullivan, J.T. Brosnan and M.E. Brosnan. “Catabolism of arginine and ornithine in the perfused rat liver: effect of dietary protein and of glucagon. Amer. J.Physiol. 278: E516-E521 (2000).
106. J.D. House, S.B. March, S. Ratnam, E.Ives, J.T. Brosnan and J.K. Friel. “Folate and Vitamin B12 status of women in Newfoundland at their first prenatal visit”. CMAJ 162: 1557-1559 (2000).
107. R.L. Jacobs, L.M. Stead, M.E. Brosnan and J.T. Brosnan “ Plasma homocysteine is decreased in the hypothyroid rat” Can. J. Physiol. Pharmacol. 78: 565-570 (2000).
108. L.M. Stead, M.E. Brosnan and J.T. Brosnan “Characterization of homocysteine metabolism in the rat liver”. Biochem. J. 350: 685-692 (2000).
109. J.T. Brosnan, M.E. Brosnan, M.E, Yudkoff, Y. Daikhin, A.Lazarow, O. Horyn, and I. Nissim. “Alanine metabolism in the perfused rat liver. Studies with (15)N. J.Biol.Chem. 276:31876-31882 (2001).
110. R.L. Jacobs, L.M. Stead, M.E. Brosnan and J.T. Brosnan. “Hyperglucagonemia in rats results in decreased plasma homocysteine and increased flux through the transsulfuration pathway in liver. J.Biol.Chem. 276: 43740-43747 (2001).
111. L.M. Stead, K.P. Au, R.L. Jacobs, M.E. Brosnan and J.T. Brosnan. “Methylation Demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate”. Amer. J. Physiol. 281: E1095-E1100 (2001).
112. J.D. House, B.N. Hall and J.T. Brosnan. “Threonine metabolism in isolated hepatocytes” Amer. J. Physiol. 281: E1300-E1307 (2001).
113. J.T. Brosnan. “Amino acids, then and now–a reflection on Sir Hans Krebs’ contribution to nitrogen metabolism”. IUBMB Life 52: 265-270 (2001).
114. J.T. Brosnan and M.E. Brosnan “Hepatic glutaminase–a special role in urea synthesis”? Nutrition 18: 455-457 (2002).
115. J.T. Brosnan, M.E. Brosnan and I. Nissim “Application of 15N to the study of hepatic nitrogen metabolism” Adv. Enz. Regul. 42: 305-315 (2002).
116. S. Ratnam, K.N. Maclean, R.L. Jacobs, M.E. Brosnan, J.P. Kraus and J.T. Brosnan. “Hormonal regulation of cystathionine beta-synthase expression in liver”. J.Biol. Chem. 277: 42912-42918 (2002).
117. A.A. Noga, L.M. Stead, Y. Zhao, M.E. Brosnan, J.T. Brosnan and D.E. Vance. “Plasma homocysteine is regulated by phospholipid methylation” J.Biol.Chem.278:5952-5955 (2003).
118. J.T. Brosnan “Interorgan amino acid transport and its regulation” J. Nutr.133: 2068S- 2072S (2003).
119. J.T. Brosnan and M.Watford “Starvation: Metabolic Changes” in the Encyclopedia of Life Sciences, Nature Publishing Group, London (2003).
120. J.T. Brosnan and V.R. Young “Integration of Metabolism: Proteins and Amino Acids” Chapter 4 of “Metabolism and Nutrition”, Eds. M.J. Gibney, I. MacDonald and H. Roche, Blackwell Publishing (2003).
121. J.T. Brosnan, M.E. Brosnan and I. Nissim. "A window into cellular metabolism: hepatic metabolism of (15)N-labelled substrates. Metab Eng. 6: 6-11 (2004).
122. J.T. Brosnan, R.L. Jacobs, L.M. Stead and M.E. Brosnan. "Methylation demand: a key determinant of homocysteine metabolism" Acta Biol Pol. 51: 405-413 (2004).
123. E.P. Wijekoon, C. Skinner, M.E. Brosnan and J.T. Brosnan. "Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes. Can J Physiol Pharmacol. 82: 506-514 (2004)
124. M.E. Brosnan and J.T. Brosnan "Renal arginine metabolism" J Nutr. 134: 2791S-2795S (2004)
125. L.M. Stead, R.L. Jacobs, M.E. Brosnan and J.T. Brosnan. "Methylation demand and homocysteine metabolism" Adv Enz Reg. 44: 321-333 (2004)
126. J.T. Brosnan. "Homocysteine and cardiovascular disease: interactions between nutrition, genetics and lifestyle. Can. J. Appl. Physiol. 29: 773-780 (2004)
127. D.J. Shields, S. Lingrell, L.B. Agellon, J.T. Brosnan and D.E. Vance “Localization-independent regulation of homocysteine secretion by phosphatidylethanolamine N-methyltransferase” J.Biol. Chem 280: 27339-27344.
128. J.T. Brosnan. “The fourth workshop on the assessment of adequate intake of dietary amino acids” J.Nutr 135: 1576S-1579S (2005).
129. R.L. Jacobs, L.M. Stead, C. Devlin, I. Tabas, M.E. Brosnan, J.T. Brosnan and D.E. Vance “Physiological regulation of phospholipids methylation alters plasma homocysteine in mice”. J. Biol. Chem. 280: 28299-28305, 2005.
130. J.T. Brosnan. “Homocysteine and Renal Disease” in “Homocysteine Metabolism-Symposia proceedings of the 4th Congress on Homocysteine Metabolism”, pp 84-94. Ed B Fowler, Publ. SPS Verlagsgesellschaft, Heilbronn, 2005.
131. E.P. Wijekoon, B. Hall, S.Ratnam, M.E. Brosnan, S.H. Zeisel and J.T. Brosnan. “Homocysteine metabolism in Type 2 Diabetes” Diabetes 54:3245-3251, 2005.
132. L. Stead, M.E. Brosnan, J.T. Brosnan, D.E. Vance and R.L. Jacobs “Is it time to re-evaluate methyl balance in humans?” Am. J. Clin. Nutr. 83:5-10, 2006.
133. J.T. Brosnan. “Metabolic design principles: chemical and physical determinants of cell chemistry” Adv Enz. Regul 45:27-36, 2005.
134. R.L. Jacobs, L.M. Stead, C. Devlin, I. Tabas, M.E. Brosnan, J.T. Brosnan and D.E. Vance. “Physiological regulation of phospholipid methylation alters plasma homocysteine in mice. J Biol Chem. 280:28299-28305; 2005.
135. J.T. Brosnan and M.E. Brosnan “Branched-chain amino acids: enzyme and substrate regulation” J Nutr. 136: 207S-211S, 2006.
136. S. Ratnam, E.P. Wijekoon, B.N. Hall, T.A. Garrow, M.E. Brosnan and J.T. Brosnan. “Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver. Am J Physiol Endocrinol Metab. 290: E933-939, 2005.
137. J.T. Brosnan and M.E. Brosnan “The sulfur-containing amino acids: an overview” J Nutr. 136: 1636S-1640S, 2006.
138. J.T. Brosnan, R. da Silva and M.E. Brosnan “Amino acids and the regulation of methyl balance in humans” Curr Opin Clin Nutr Metab Care 10: 52-57, 2007.
139. S.H. Mudd, J.T. Brosnan, M.E. Brosnan, R.L. Jacobs, S.P. Stabler, R.H. Allen, D.E. Vance, C. Wagner “Methyl balance and transmethylation fluxes in humans” Am J Clin Nutr 85: 19-25, 2007.
140. M.E. Brosnan and J.T. Brosnan “Orotic acid excretion and arginine metabolism” J Nutr 137: 1656S-1661S, 2007.
141. M.E. Brosnan, E.E. Edison, R. da Silva and J.T. Brosnan “New insights into creatine synthesis and function” Adv Enz Regul 47: 252-260, 2007.
142. J.T. Brosnan and M.E. Brosnan “Creatine: Endogenous metabolite, dietary and therapeutic supplement” Ann Rev Nutr 27: 341-261, 2007.
143. M.E. Brosnan and J.T. Brosnan “Protein and Amino Acid Metabolism” in “Textbook of Hepatology: From Basic Science to Clinical Practice”, 3rd Edition (Eds JP Benhamou et al.) Blackwell Publishing.
144. E.P. Wijekoon, M.E. Brosnan and J.T. Brosnan “Homocysteine Metabolism in Diabetes” Biochem Soc Trans 35: 1175-1179, 2007.
145. J.T. Brosnan and M.E. Brosnan “Glutathione and the Sulfur-Containing Amino Acids---an Overview”, in “Glutathione and the Sulfur-Containing Amino Acids” (Eds R Masella and G Mazza) John Wiley (in press).
146. E.E. Edison, M.E. Brosnan, C. Meyer and J.T. Brosnan “Creatine Synthesis: Production of Guanidinoacetate by the rat and human kidney in vivo. Am J Physiol Renal 293: F1799-1804, 2008.
147. Y. Zhao, N. Methot, B. Kennedy, G. Francis, J.T. Brosnan and D.E. Vance “Impaired Hepatic Phosphatidylcholine Biosynthesis Altered Plasma VLDL and Attenuated Atherosclerosis in LDLr-/- Mice. Atherosclerosis, Thrombosis and Vascular Biology (Submitted).
148. R. da Silva, I. Nissim, M.E. Brosnan, J.T. Brosnan “Creatine synthesis: Hepatic metabolism of guanidinoacetate and creatine in the rat, in vivo and in vitro”. Am J Physiol Endocrinol Metab (In Revision).
149. M.E. Brosnan and J.T. Brosnan “Hepatic glutamate metabolism: a tale of two hepatocytes”. Am J Clin Nutr (Submitted).
150. J.T. Brosnan and A.P. Halestrap “From metabolic cycles to compartmentation: another first for Krebs” The Biochemist 30: 24-28, 2008.